Succimer, also known as DMSA (meso-2,3-dimercaptosuccinic acid), is a sulfur-containing organic compound with strong metal-chelating properties. It is the meso isomer of 2,3-dimercaptosuccinic acid, widely used as an oral heavy metal antidote and pharmaceutical intermediate. Succimer forms water-soluble complexes with lead, arsenic, mercury and other heavy metals, promoting their excretion from the body.

2. Basic Specifications

• Product Name: Succimer

• Alias: DMSA, meso-2,3-Dimercaptosuccinic Acid

• CAS Number: 304-55-2

• Molecular Formula: C₄H₆O₄S₂

• Molecular Weight: 182.22

• Purity: ≥98% (HPLC)

• Appearance: White to off-white crystalline powder

• Odor: Characteristic mercaptan (sulfur) odor

• Melting Point: 196–198 °C (dec.)

• Solubility: Slightly soluble in water; soluble in DMSO, methanol, ethanol

• Grade: Pharmaceutical Grade / Research Grade / Industrial Grade

3. Mechanism & Benefits

• Heavy Metal Chelation: Binds strongly with lead, mercury, arsenic, cadmium, increasing urinary excretion.

• Oral Bioavailability: Effective when administered orally, more convenient than injectable chelators.

• Lead Poisoning Treatment: FDA-approved for pediatric and adult lead poisoning (blood lead >45 μg/dL).

• Low Toxicity: Better safety profile compared to traditional chelators like BAL.

• Research Tool: Used in toxicology, pharmacology, and heavy metal detoxification studies.

4. Applications

• Pharmaceuticals: Active pharmaceutical ingredient (API) in oral lead poisoning treatments (e.g., CHEMET).

• Medical Research: Chelation therapy research, heavy metal toxicity studies.

• Veterinary Medicine: Treatment of heavy metal poisoning in animals.

• Industrial Use: Metal ion removal in wastewater and chemical processing.

• Laboratory Reagent: Standard chelating agent for analytical chemistry.

5. Packaging & Storage

• Packaging: 1kg/aluminum foil bag, 5kg/bag, 25kg/drum (custom packaging available)

• Storage: Store in a cool, dry, sealed place; keep away from oxidizing agents and direct sunlight.

• Temperature: Recommended storage at -20 °C for long-term stability.

• Shelf Life: 24 months under proper storage conditions.

6. Our Advantages

• High Purity: ≥98% HPLC, strictly quality controlled.

• Factory Direct Supply: Competitive price, stable stock.

• Full Documentation: COA, MSDS, HPLC, NMR available.

• Custom Service: Custom packaging, labeling, and synthesis.

• Global Shipping: Fast delivery to North America, Europe, Asia, etc.